Opioid-induced hyperalgesia: when pain killers make pain worse
نویسندگان
چکیده
منابع مشابه
Opioid-induced hyperalgesia: pain hurts?
In the current issue of the British Journal of Anaesthesia, Shin and colleagues report that propofol used for the maintenance of general anaesthesia may prevent remifentanilinduced hyperalgesia. In their study, a comparison of propofol and sevoflurane combined with either high dose or low dose of remifentanil for the maintenance of general anaesthesia in breast cancer surgery was conducted. The...
متن کاملOpioid-induced hyperalgesia--worsening pain in opioid-dependent patients.
Patients with chronic opioid use are commonly treated in the emergency department (ED). Opioid-induced hyperalgesia occurs in patients consuming opioids chronically and is a paradoxical response of increased pain with opioid administration. It is difficult to diagnose and is often underrecognized, and therapies are unconventional. We report a case of a young service member with chronic pain and...
متن کاملComparison of pain models to detect opioid-induced hyperalgesia
OBJECTIVE Chronic opioid therapy may be associated with hyperalgesia. Our objective was to determine if opioid-induced hyperalgesia detection sensitivity is dependent on the stimulus used to detect it. METHODS This open design study compared the detection of hyperalgesia in opioid-dependent subjects (n = 16) and healthy control subjects (n = 16) using the following pain stimuli: cold pain, el...
متن کاملOpioid induced hyperalgesia: clinical implications for the pain practitioner.
Opioids have been and continue to be used for the treatment of chronic pain. Evidence supports the notion that opioids can be safely administered in patients with chronic pain without the development of addiction or chemical dependency. However, over the past several years, concerns have arisen with respect to administration of opioids for the treatment of chronic pain, particularly non-cancer ...
متن کاملPAIN Opioid-induced hyperalgesia in a mice model of orthopaedic pain: preventive effect of ketamine
Postoperative pain management is a great challenge because it is a critical part of a patient’s recovery. 2 Bone injury is often accompanied by acute pain that can be clearly diminished by morphine use. 4 However, although opioids are among the most effective analgesics in humans, there is growing evidence showing that they also induce abnormal and prolonged pain states after acute or chronic a...
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ژورنال
عنوان ژورنال: Case Reports
سال: 2014
ISSN: 1757-790X
DOI: 10.1136/bcr-2014-204551